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Phylogenetic inference of relative monthly incidence of SARS-CoV-2 under endemic conditions. (A) Time tree extending from the most recent common ancestor (MRCA) to current day taxa based on the phylogenetic divergence of HCoV coronaviruses. Empirical relative monthly incidences of (B) HCoV-NL63, (C) HCoV-229E, (D) HCoV-HKU1, and (E) HCoV-OC43 and (F) ancestral- and descendant-state analytical estimates of relative monthly incidences of SARS-CoV-2 in Trøndelag, Norway.
