Table 3.
Cardiovascular variables during baseline and CPT/PLCB.
| RA |
N2O |
||||
|---|---|---|---|---|---|
| Baseline | CPT/PLCB | Baseline | CPT/PLCB | ||
| SBP, mmHg | CPT[1st] | 117.3 ± 10.8 | 135.8 ± 16.2* | 114.3 ± 8.1 | 129.5 ± 12.2*$ |
| CPT + CC | 119.4 ± 12.3 | 135.6 ± 17.8* | 117.1 ± 10.2 | 137.8 ± 14.9* | |
| PLCB + CC | 119.0 ± 13.4 | 121.9 ± 11.9 | 119.4 ± 9.6 | 124.1 ± 13.1 | |
| DBP, mmHg | CPT[1st] | 73.2 ± 9.3 | 88.7 ± 10.6* | 71.4 ± 4.9 | 86.3 ± 12.1* |
| CPT + CC | 78.0 ± 8.0 | 91.3 ± 12.5* | 74.3 ± 5.3 | 90.3 ± 11.3* | |
| PLCB + CC | 74.9 ± 6.2 | 75.0 ± 7.6 | 75.1 ± 4.9 | 76.8 ± 8.4 | |
| HR, bpm | CPT[1st] | 65.5 ± 9.1 | 71.6 ± 12.1 | 64.7 ± 10.8 | 62.5 ± 18.2$ |
| CPT + CC | 64.4 ± 7.6 | 71.0 ± 12.1 | 58.8 ± 18.9 | 70.4 ± 8.8 | |
| PLCB + CC | 63.7 ± 8.4 | 63.4 ± 8.6 | 62.7 ± 10.9 | 61.1 ± 10.1 | |
| SpO2, % |
CPT[1st] | 98.8 ± 1.1 | 99.1 ± 0.9 | 99.5 ± 0.6 | 99.7 ± 0.6$ |
| CPT + CC | 98.5 ± 1.1 | 99.1 ± 0.9 | 99.8 ± 0.4 | 99.9 ± 0.3$ | |
| PLCB + CC | 98.5 ± 1.0 | 98.7 ± 0.9 | 99.8 ± 0.4 | 99.8 ± 0.4$ | |
| β-stiffness, a.u. | CPT[1st] | 1.9 ± 1.6 | 5.7 ± 8.0* | 1.3 ± 0.5 | 2.8 ± 1.4* |
| CPT + CC | 3.0 ± 4.9 | 7.2 ± 9.1* | 1.2 ± 0.3 | 2.0 ± 0.8*$ | |
| PLCB + CC | 2.4 ± 3.2 | 2.9 ± 4.2 | 1.5 ± 0.7 | 1.4 ± 1.1 | |
Values are mean ± S.D. SBP indicates systolic blood pressure; DBP, diastolic blood pressure; HR, heart rate; SpO2, percutaneous oxygen saturation; CPT, cold pressor test; PLCB, placebo test; CC, central command. Each variable was compared between conditions under RA and N2O and between baseline and CPT/PLCB using two-way repeated ANOVA (n = 15). *, vs baseline at p < 0.05; $, vs RA at p < 0.05 by post-hoc test (Tukey test).