Table 2.
Histopathological evaluation results of ADR and/or NAC applications on liver tissue
|
Control (n = 7) Median(Min–Max) |
NAC (n = 7) Median(Min–Max) |
ADR (n = 7) Median(Min–Max) |
ADR + NAC (n = 7) Median(Min–Max) |
P* | |
|---|---|---|---|---|---|
| Sinusoid dilatation | 0.20(0.00–0.30)b | 0.20(0.00–0.40)b | 2.10(1.40–2.60)a | 0.90(0.50–1.50)a b | < 0.001 |
| Hepatocyte vacuolization | 0.20(0.00–0.50)b | 0.20(0.10–0.40)b | 2.20(1.70–2.60)a | 0.90(0.60–1.30)a b | < 0.001 |
| Foci of inflammation | 0.00(0.00–0.10)b | 0.10(0.00–0.20)b | 2.40(1.90–2.70)a | 0.60(0.50–1.60)a b | < 0.001 |
| Degenerated hepatocyte cords | 0.20(0.00–0.30)b | 0.20(0.00–0.40)b | 2.40(1.70–2.60)a | 0.70(0.50–1.80)a b | < 0.001 |
| Hemorrhagic areas | 0.00(0.00–0.10)b | 0.00(0.00–0.20)b | 1.90(0.80–2.30)a | 0.50(0.30–1.30)a b | < 0.001 |
Data are presented as median (min–max)
a: Compared with the control group (p < 0.05),
b: Compared with the ADR group (p < 0.05)
p* Kruskal Wallis