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. 2023 Jul 21;14(1):208–222. doi: 10.1007/s13346-023-01393-w

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Fig. 3 — Optical characterisation of donepezil HCl-loaded MAPs. A Light microscopy images of MAPs. B SEM images of MAPs. C Reduction in needles height after being compressed for 30 s with a 32 N force (means + SD, n = 20). Insertion capabilities of donepezil-loaded MAPs into D Parafilm^®M (measured by holes created in each layer) (means ± SD, n = 3), Parafilm^®M and full thickness (FT) porcine skin (measured by OCT) (means + SD, n = 20). Representative OCT images of MAPs insertion into F Parafilm^®M and G full-thickness porcine skin. H In situ skin dissolution of donepezil-loaded MAPs at defined time periods