Table 2.
Changes in anxiety and depression symptoms in patients with at least mild baseline symptoms. Patients with at least mild baseline symptoms (baseline GAD-7a or PHQ-8b scores≥5) are included in the analyses.
| Measure and sample | Responses, n |
Baseline score, mean (SD) |
Last score, mean (SD) | Changes from baseline (%) |
Mean difference (95% CI) |
Effect size (Cohen d) | Baseline score, median |
Last score, median | Paired sample Wilcoxon test |
P value |
|
| GAD-7 | |||||||||||
|
|
Baseline GAD-7 score≥5 | 1602 | 12.20 (4.55) | 6.87 (4.82) | 43.69 | –5.34 (–5.59 to –5.09) | 1.05 | 12 | 6 | V=1099198 | <.001 |
|
|
Baseline GAD-7 score≥10 | 1074 | 14.72 (3.27) | 8.00 (5.00) | 45.65 | –6.71 (–7.03 to –6.40) | 1.30 | 14 | 7 | V=1039814 | <.001 |
| PHQ-8 | |||||||||||
|
|
Baseline PHQ-8 score≥5 | 1572 | 12.78 (4.90) | 7.33 (5.47) | 42.64 | –5.45 (–5.73 to –5.18) | 0.98 | 12 | 6 | V=519504 | <.001 |
|
|
Baseline PHQ-8 score≥10 | 1097 | 15.22 (3.74) | 8.37 (5.69) | 45.01 | –6.85 (–7.18 to –6.52) | 1.23 | 15 | 8 | V=482402 | <.001 |
aGAD-7: Generalized Anxiety Disorder–7.
bPHQ-8: Patient Health Questionnaire–8.