Table 4.

Risk score transition—differences in absolute risk and heart age^a.

Biological age (years)	Risk score	Healthy personab		Average personac		Unhealthy personad
		Absolute 10-year risk (%)	Heart age (years)	Absolute 10-year risk (%)	Heart age (years)	Absolute 10-year risk (%)	Heart age (years)
37	FRSe	1.23	31	2.17	37	8.96	60
38	FRS	1.33	32	2.35	38	9.68	62
39	FRS	1.44	33	2.54	39	10.44	63
40	SCORE2f	1.06	31	1.92	40	8.77	66
41	SCORE2	1.14	32	2.04	41	9.07	66
42	SCORE2	1.22	33	2.17	42	9.37	67
67	SCORE2	7.38	63	9.72	67	21.02	81
68	SCORE2	7.91	64	10.30	68	21.68	82
69	SCORE2	8.49	65	10.92	69	22.36	82
70	SCORE2-OPg	7.07	66	10.15	70	27.49	84
71	SCORE2-OP	7.68	67	10.98	71	28.56	84
72	SCORE2-OP	8.33	68	11.87	72	29.67	85

^aFor primary prevention, Framingham Risk Score, Systematic Coronary Risk Evaluation 2 (SCORE2), and SCORE2 in Older Persons were used for risk estimation. Differences in absolute risk estimates were apparent in the transition zones between scores, particularly in high-risk individuals. Estimating the heart age instead of the absolute risk numbers helped smooth the transitions between scores.

^bHealthy persona: male, nonsmoker, nondiabetic, systolic blood pressure 125 mm Hg, no blood pressure treatment, total cholesterol 170 mg/dL, high-density lipoprotein cholesterol 70 mg/dL.

^cAverage persona: male, nonsmoker, nondiabetic, systolic blood pressure 130 mm Hg, no blood pressure treatment, total cholesterol 200 mg/dL, high-density lipoprotein cholesterol 50 mg/dL.

^dUnhealthy persona: male, smoker, nondiabetic, systolic blood pressure 155 mm Hg, no blood pressure treatment, total cholesterol 250 mg/dL, high-density lipoprotein cholesterol 40 mg/dL.

^eFramingham Risk Score.

^fSCORE2: Systematic Coronary Risk Evaluation 2.

^gSCORE2-OP: Systematic Coronary Risk Evaluation 2–Older Persons.