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Scheme of the glioma tumor microenvironment and biomarkers. (a) Tumor-associated macrophages, regular T cells, monocytes, neutrophils, neurons, pericytes, glioma cells, inflammatory cytokines, astrocytes, extracellular vesicles, blood vessels, dendric cells, and NK cells are present in the glioma tumor microenvironment. (b) The biomarkers are B7-H3, CD70, CD147, CAIX, CSPG4, GD2, EGFRVIII, HER2, IL13Rα2, MMP2, and TROP2 (created with the free trail of BioRender).
