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. 2023 Dec 7;16(12):1695. doi: 10.3390/ph16121695

Table 3.

MIC values of synthetic thiosulfinates, TGS and commercial drugs against C. albicans.

Antimycotic Drug C. albicans, MIC ± CI (95%)
μg/mL μM
Synthetic thiosulfinates
DMTS 2.68 ± 0.57 24 ± 5.1
DETS 0.72 ± 0.16 5.2 ± 1.15
DPTS 0.69 ± 0.26 4.1 ± 1.54
DATS 3.31 ± 1.10 20 ± 6.65
TGSs
C115H MGL/methiin 1.11 ± 0.22 10 ± 1.98
C115H MGL/ethiin 0.41 ± 0.09 3 ± 0.66
C115H MGL/propiin 0.36 ± 0.09 2.2 ± 0.55
C115H MGL/alliin 0.39 ± 0.07 2.4 ± 0.43
Commercial drugs
AmpB 0.46 ± 0.25 0.5 ± 0.27
FLC 1.06 ± 0.21 3.5 ± 0.69
5-FC 0.16 ± 0.03 1.2 ± 0.22