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Schematic diagram of the generation of immune serum, and the challenge with DENV-2 involved in the A129 mouse model. A129 mice were immunized either intraperitoneally or subcutaneously with a single dose of Dengvaxia or PBS. After vaccination, serum samples were collected on days 0 and 14 for antibody detection and mice were then challenged with the DENV-2 virus. Other activities are indicated in the diagram above.
