TABLE 1.
MICs (milligrams per liter) of various antimicrobial agents for HN891 (an overproducer of the Acr pump), SH5014 (parent strain), and SH7616 (an acr mutant)
| Antimicrobial agent | MIC for indicated strain
|
||
|---|---|---|---|
| HN891 | SH5014 | SH7616 | |
| Sodium dodecyl sulfate | >16,000 | >16,000 | 64 |
| Sodium deoxycholate | >16,000 | >16,000 | 1,024 |
| Sodium cholate | >64,000 | >64,000 | 1,024 |
| Triton X-100 | >64,000 | >64,000 | 256 |
| Crystal violet | >256 | >256 | 1 |
| Acriflavine | >128 | >128 | 32 |
| Fusidic acid | >512 | 512 | 4 |
| Novobiocin | >256 | 64 | 1 |
| Erythromycin A | 1,024 | 512 | 8 |
| Rifampin | 16 | 16 | 8 |
| Tetracycline | 2 | 1 | 0.25 |
| Chloramphenicol | 8 | 4 | 0.25 |
| Norfloxacin | 1 | 0.24 | 0.03 |
| Nalidixic acid | 8 | 4 | 0.5 |
| Penicillin G | 32 | 8 | 0.25 |