TABLE 2.
Strain classification by hif genotype and hemagglutination phenotype
| Straina | Sourceb | Classc | hifAd | hicABe | HAf |
|---|---|---|---|---|---|
| Hib Eagan | CSF, meningitis patient | IV | +, (AT)10 | − | + |
| Rd | L | I | − | − | − |
| Type a | L | V | + | − | + |
| Type b | L | V | + | − | + |
| Type c | L | VII | + | − | + |
| Type d | L | I | − | − | − |
| Type e | L | I | − | − | − |
| Type f | L | IIIb | −, (AT)5 | − | ± |
| INT1 | Blood, meningitis patient | VI | +, (AT)4 | + | − |
| R2777 | CSF | I | − | − | − |
| R3001 | Bronchial infection | IIa | − | + | − |
| R1965 | L | IIa | − | + | − |
| U11 | CSF | IIa | − | + | − |
| C2836 | Otitis media | IIa | − | + | − |
| C2840 | Tracheal infection | IIb | − | + | ± |
| Hib C2843 | Otitis media | V | + | − | − |
| C2853 | Sputum | IIa | − | + | − |
| C2859 | CSF | IIb | − | + | − |
| C2861 | CSF | IIIa | −, (AT)4 | + | ± |
| Hib AM30g | CSF, meningitis patient | V | +, (AT)10 | − | + |
Types a to f are the reference strains for each capsular serotype. All other isolates except those designated Hib are nontypeable.
L, laboratory reference strain.
hif genotype classification (Fig. 6).
Presence (+) or absence (−) of an intact hifA gene and number of AT repeats in the hifA promoter, if known. For strains showing phase variation, the number of repeats is that in a piliated variant; for INT1, C2861, and type f, the number of repeats is that in the original isolate.
Presence (+) or absence (−) of intact copies of both hicA and hicB within the region between purE and pepN.
HA, hemadsorption ability after enrichment for adherent variants (see Materials and Methods). +, macroagglutination; ±, microagglutination (see Materials and Methods).