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. 2023 Nov 29;73:103615. doi: 10.1016/j.breast.2023.103615

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© 2023 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 2 — (A–C) Individual-level estimated modified lifetime risks (eLTR) for breast cancer (BC) depending on CanRisk estimation model and genetic test result, using the BASIC model as baseline. (D–F) Individual-level estimated 10-year risks (e10YR) for BC, which consider the age at the time of consultation, depending on CanRisk estimation model and genetic test result. (A, D) BASIC vs NGRF (B, E) BASIC vs PRS (C, F) BASIC vs FULL. NGRF = non-genetic risk factors, PRS = polygenic risk score, FULL = comprehensive model including PRS₃₀₆ and NGRFs.