Table 2.

CanRisk-based BC risk estimation models used in this study. FH = family history of breast, ovarian, prostate and pancreatic cancer, age information on unaffected family members, information on birth cohort; PV status = genetic test result from gene panel analyses for pathogenic variants (PVs) in moderate- or high-risk predisposition genes (ATM, BRCA1, BRCA2, PALB2, CHEK2); NGRF = non-genetic risk factors (age of menarche, parity, age at first live birth, use of oral contraception, use of menopause hormone therapy, body mass index, daily alcohol intake, height). PRS₃₀₆ = 306 variant-based BRIDGES PRS⁷.

Risk estimation model	Risk factor category
	FH	PV status	NGRF	PRS306
BASIC	●	●
NGRF	●	●	●
PRS	●	●		●
FULL	●	●	●	●