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ATG5 can restore the inhibitory effect of Erastin on HCC. A The ATG5 Plasmid was transfected into Huh7 cells for 12h, and the expression level of ATG5 was detected by Western blot. B Erastin was applied to HuH7 or HepG2 cells that had been transfected with WTAP siRNA and ATG5 plasmid alone or together. Overall cellular proliferation of HepG2 tested by MTT assay. The mean±SD was used as the value of three independent experiments. *p<0.05; **p<0.01; ***p<0.001.
