YTHDC2 KD impaired HCC ferroptosis. A Expression of m6A readers in HepG2 cells detected by western blot. B The YTHDC2 siRNA was transfected into Huh7 cells for 12 h, and the expression level of YTHDC2 was detected by Western blot. C The YTHDC2 plasmid was transfected into Huh7 cells for 12 h, and the expression level of YTHDC2 was detected by Western blot. D Expression of ATG5 and YTHDC2 in Huh7 and HepG2 cells detected by western blot. E-F The level of GSH, iron, MDA, and ROS were tested detected by kits. The mean±SD was used as the value of three independent experiments. *p<0.05; **p<0.01; ***p<0.001.