Figure 8.

Attenuation of CS-induced lung inflammation in WT germ-free mice after oral transplantation with fecal microbiota from Nlrp6-/- mice. (A) WT germ-free (GF) mice were colonized with WT or Nlrp6-/- microbiota at weaning and let 5 weeks for microbiota implantation for before CS exposure. (B) BALF total cell and (C) neutrophil counts. (D-F) BALF MPO, CXCL1 and CXCL5 levels. Data are representative of two experiments and are expressed as mean values ± SEM (n= 4-6 mice per group), ns, non-significant, **p < 0.01, ***p < 0.001, ****P<0.0001.