Table 1.
Baseline Characteristics of Individuals Stratified by Tertiles of Baseline NPAR Levels
| Variables | Total | NPAR | P-value | ||
|---|---|---|---|---|---|
| (n = 1966) | < 1.64 (n = 651) | 1.64–1.93 (n = 655) | ≥ 1.93 (n = 660) | ||
| Age (years) | 46.83 ± 15.12 | 43.05 ± 14.15 | 45.88 ± 14.61 | 51.51 ± 15.35 | < 0.001 |
| Men (n, %) | 1186 (60.3%) | 431 (66.2%) | 397 (60.6%) | 358 (54.2%) | < 0.001 |
| Body mass index (kg/m2) | 21.64 ± 3.13 | 21.36 ± 3.06 | 21.81 ± 3.13 | 21.76 ± 3.18 | 0.019 |
| History of diabetes (n, %) | 491 (25.0%) | 84 (12.9%) | 160 (24.4%) | 247 (37.4%) | < 0.001 |
| History of CVD (n, %) | 662 (33.7%) | 193 (29.6%) | 205 (31.3%) | 264 (40.0%) | < 0.001 |
| Charlson comorbidity index | 3.46 ± 1.79 | 3.03 ± 1.56 | 3.32 ± 1.73 | 4.04 ± 1.93 | < 0.001 |
| Hemoglobin (g/L) | 100.65 ± 21.89 | 107.11 ± 20.96 | 101.47 ± 20.97 | 93.43 ± 21.56 | < 0.001 |
| Serum albumin (g/L) | 36.77 ± 5.06 | 40.15 ± 3.90 | 37.56 ± 3.57 | 32.65 ± 4.44 | < 0.001 |
| Uric acid (µmol/L) | 428.67 ± 95.00 | 439.01 ± 94.94 | 429.51 ± 89.70 | 417.61 ± 99.04 | < 0.001 |
| Phosphorus (mmol/L) | 1.41 ± 0.41 | 1.44 ± 0.42 | 1.40 ± 0.38 | 1.39 ± 0.42 | 0.106 |
| Corrected-calcium (mmol/L) | 2.67 ± 1.55 | 2.52 ± 1.27 | 2.65 ± 1.54 | 2.82 ± 1.79 | 0.002 |
| Total cholesterol (mmol/L) | 5.01 ± 1.33 | 5.00 ± 1.26 | 4.97 ± 1.28 | 5.06 ± 1.44 | 0.415 |
| Triglyceride (mmol/L) | 1.40 (1.00–2.01) | 1.42 (1.02–2.04) | 1.36 (1.00–1.90) | 1.42 (0.97–2.07) | 0.319 |
| HDL-C (mmol/L) | 1.23 ± 0.43 | 1.26 ± 0.44 | 1.21 ± 0.38 | 1.22 ± 0.48 | 0.085 |
| LDL-C (mmol/L) | 2.96 ± 1.00 | 2.92 ± 0.96 | 2.94 ± 0.93 | 3.00 ± 1.10 | 0.286 |
| hs-CRP (mg/L) | 1.66 (0.58–5.21) | 1.16 (0.49–3.21) | 1.67 (0.63–5.26) | 2.51 (0.80–8.39) | < 0.001 |
| Neutrophil (109/L) | 4.56 ± 1.72 | 3.70± 1.21 | 4.52 ± 1.38 | 5.43 ± 2.00 | < 0.001 |
| Lymphocyte (109/L) | 1.53 ± 0.58 | 1.75 ± 0.62 | 1.50 ± 0.52 | 1.34 ± 0.52 | < 0.001 |
| Monocyte (109/L) | 0.45 ± 0.20 | 0.44 ± 0.19 | 0.43 ± 0.19 | 0.47 ± 0.23 | 0.012 |
| Total Kt/V | 2.48 ± 0.80 | 2.48 ± 0.76 | 2.52 ± 0.92 | 2.45 ± 0.70 | 0.357 |
| RRF (mL/min/1.73 m2) | 3.31 (1.95–5.25) | 3.48 (2.03–5.50) | 3.47 (2.15–5.28) | 2.91 (1.55–4.83) | < 0.001 |
| Serum creatinine (µmol/L) | 716 (581–920) | 747 (604–948) | 729 (594–938) | 681 (547–858) | < 0.001 |
Note: P<0.05 is considered statistically significant.
Abbreviations: NPAR, neutrophil percentage-to-albumin ratio; CVD, cardiovascular disease; LDL-C, low density lipoprotein cholesterol; HDL-C, high density lipoprotein cholesterol; hs-CRP, high sensitive C-reactive protein; RRF, residual renal function; Kt/V, urea clearance index.