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. 2023 Dec 21;16:6271–6281. doi: 10.2147/JIR.S437256

Table 3.

The Association of NPAR with All-Cause and Cardiovascular Mortality

Model 1a Model 2b Model 3c
HR (95% CI) P-value HR (95% CI) P-value HR (95% CI) P-value
All-cause mortality
Continuous NPARd 2.54 (2.09–3.07) <0.001 1.74 (1.41–2.13) <0.001 1.56 (1.18–2.05) 0.002
Tertile 1 1.0 1.0 1.0
Tertile 2 1.35 (1.06–1.73) 0.015 1.21 (0.94–1.54) 0.136 1.14 (0.85–1.53) 0.369
Tertile 3 2.51 (2.01–3.14) <0.001 1.71 (1.36–2.15) <0.001 1.51 (1.14–1.98) 0.004
P for trend <0.001 <0.001 0.002
Cardiovascular mortality
Continuous NPARd 2.54 (1.94–3.32) <0.001 1.70 (1.27–2.27) <0.001 1.57 (1.07–2.28) 0.020
Tertile 1 1.0 1.0 1.0
Tertile 2 1.37 (0.97–1.94) 0.073 1.21 (0.85–1.71) 0.294 1.17 (0.77–1.78) 0.452
Tertile 3 2.55 (1.86–3.50) <0.001 1.74 (1.26–2.39) 0.001 1.57 (1.07–2.31) 0.022
P for trend <0.001 <0.001 0.016

Notes: aUnadjusted model. bAdjusted for age, gender, body mass index. cAdjusted for model 2 covariates and Charlson comorbidity index, hemoglobin, corrected calcium, phosphorus, total cholesterol, triglycerides, hs-CRP, total Kt/V and residual renal function. dPer unit increment in NPAR levels. P<0.05 is considered statistically significant.

Abbreviations: HR, hazard ratio; CI, confidence interval.