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. 2014 Jan 31;2014(1):CD008265. doi: 10.1002/14651858.CD008265.pub2

Comparison 1. Endoscopic versus open or mini‐open carpal tunnel release.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Overall improvement at 3 months or less 1   Risk Ratio (M‐H, Random, 95% CI) Totals not selected
1.1 ECTR vs modified OCTR 1   Risk Ratio (M‐H, Random, 95% CI) 0.0 [0.0, 0.0]
2 Overall satisfaction at 3 months or less 1   Mean Difference (IV, Random, 95% CI) Totals not selected
2.1 ECTR vs modified OCTR 1   Mean Difference (IV, Random, 95% CI) 0.0 [0.0, 0.0]
3 Symptom Severity Scale (Levine) at 3 months or less 5 551 Std. Mean Difference (Random, 95% CI) ‐0.13 [‐0.47, 0.21]
3.1 ECTR vs standard OCTR 4 531 Std. Mean Difference (Random, 95% CI) ‐0.09 [‐0.48, 0.30]
3.2 ECTR vs modified OCTR 1 20 Std. Mean Difference (Random, 95% CI) ‐0.37 [‐1.01, 0.27]
4 Function Status Scale at 3 months or less 5 551 Std. Mean Difference (Random, 95% CI) ‐0.23 [‐0.60, 0.14]
4.1 ECTR vs standard OCTR 4 531 Std. Mean Difference (Random, 95% CI) ‐0.19 [‐0.61, 0.23]
4.2 ECTR vs modified OCTR 1 20 Std. Mean Difference (Random, 95% CI) ‐0.48 [‐1.14, 0.17]
5 Pain at 3 months or less (corr = 0.5) 4 358 Std. Mean Difference (Random, 95% CI) ‐0.21 [‐0.72, 0.30]
5.1 ECTR vs standard OCTR 2 278 Std. Mean Difference (Random, 95% CI) ‐0.41 [‐0.65, ‐0.18]
5.2 ECTR vs modified OCTR 2 80 Std. Mean Difference (Random, 95% CI) 0.01 [‐1.07, 1.08]
6 Pain at 3 months or less (corr = 0.9) 4   Std. Mean Difference (Random, 95% CI) ‐0.20 [‐0.58, 0.18]
6.1 ECTR vs standard OCTR 2   Std. Mean Difference (Random, 95% CI) ‐0.41 [‐0.65, ‐0.18]
6.2 ECTR vs modified OCTR 2   Std. Mean Difference (Random, 95% CI) 0.00 [‐0.48, 0.48]
7 Pain at 3 months or less (corr = 0.1) 4   Std. Mean Difference (Random, 95% CI) ‐0.20 [‐0.74, 0.34]
7.1 ECTR vs standard OCTR 2   Std. Mean Difference (Random, 95% CI) ‐0.41 [‐0.65, ‐0.18]
7.2 ECTR vs modified OCTR 2   Std. Mean Difference (Random, 95% CI) 0.01 [‐1.43, 1.46]
8 Pain (dichotomous) at 3 months or less 5 348 Risk Ratio (M‐H, Random, 95% CI) 0.69 [0.33, 1.45]
8.1 ECTR vs standard OCTR 4 288 Risk Ratio (M‐H, Random, 95% CI) 0.49 [0.21, 1.15]
8.2 ECTR vs modified OCTR 1 60 Risk Ratio (M‐H, Random, 95% CI) 2.0 [1.01, 3.95]
9 Numbness (dichotomous) at 3 months or less 5   Risk Ratio (M‐H, Random, 95% CI) Subtotals only
9.1 ECTR vs OCTR 5 435 Risk Ratio (M‐H, Random, 95% CI) 1.14 [0.76, 1.71]
10 Grip strength at 3 months or less 6 560 Std. Mean Difference (Random, 95% CI) 0.36 [0.09, 0.63]
10.1 ECTR vs standard OCTR 5 540 Std. Mean Difference (Random, 95% CI) 0.40 [0.10, 0.71]
10.2 ECTR vs modified OCTR 1 20 Std. Mean Difference (Random, 95% CI) 0.14 [‐0.48, 0.76]
11 Overall improvement at more than 3 months 4 317 Risk Ratio (M‐H, Random, 95% CI) 1.04 [0.95, 1.14]
11.1 ECTR vs standard OCTR 3 257 Risk Ratio (M‐H, Random, 95% CI) 1.05 [0.96, 1.15]
11.2 ECTR vs modified OCTR 1 60 Risk Ratio (M‐H, Random, 95% CI) 0.89 [0.59, 1.35]
12 Overall satisfaction at more than 3 months 1   Mean Difference (IV, Random, 95% CI) Totals not selected
12.1 ECTR vs standard OCTR 1   Mean Difference (IV, Random, 95% CI) 0.0 [0.0, 0.0]
13 Symptom Severity Scale (Levine) at more than 3 months 2   Mean Difference (IV, Random, 95% CI) Subtotals only
13.1 ECTR vs standard OCTR 2 273 Mean Difference (IV, Random, 95% CI) 0.02 [‐0.18, 0.22]
14 Function Status Scale at more than 3 months 2   Mean Difference (IV, Random, 95% CI) Subtotals only
14.1 ECTR vs standard OCTR 2 273 Mean Difference (IV, Random, 95% CI) 0.01 [‐0.14, 0.16]
15 Pain at more than 3 months 1   Mean Difference (IV, Random, 95% CI) Subtotals only
15.1 ECTR vs standard OCTR 1 128 Mean Difference (IV, Random, 95% CI) ‐5.20 [‐12.65, 2.25]
16 Pain (dichotomous) at more than 3 months 6   Risk Ratio (M‐H, Random, 95% CI) Subtotals only
16.1 ECTR vs standard OCTR 6 407 Risk Ratio (M‐H, Random, 95% CI) 0.88 [0.57, 1.38]
17 Numbness at more than 3 months 1 192 Mean Difference (IV, Random, 95% CI) 0.06 [‐0.04, 0.16]
17.1 ECTR vs standard OCTR 1 192 Mean Difference (IV, Random, 95% CI) 0.06 [‐0.04, 0.16]
18 Numbness (dichotomous) at more than 3 months 4   Risk Ratio (M‐H, Random, 95% CI) Subtotals only
18.1 ECTR vs standard OCTR 4 234 Risk Ratio (M‐H, Random, 95% CI) 0.64 [0.31, 1.35]
19 Grip strength at more than 3 months 2 56 Std. Mean Difference (IV, Random, 95% CI) 1.13 [0.56, 1.71]
19.1 ECTR vs standard OCTR 2 56 Std. Mean Difference (IV, Random, 95% CI) 1.13 [0.56, 1.71]
20 Time to return to work 4   Mean Difference (IV, Random, 95% CI) Subtotals only
20.1 ECTR vs standard OCTR 4 274 Mean Difference (IV, Random, 95% CI) ‐8.10 [‐14.28, ‐1.92]
21 Recurrence 12 1228 Risk Ratio (M‐H, Random, 95% CI) 0.81 [0.46, 1.42]
21.1 ECTR vs standard OCTR 10 1132 Risk Ratio (M‐H, Random, 95% CI) 0.75 [0.41, 1.36]
21.2 ECTR vs modified OCTR 2 96 Risk Ratio (M‐H, Random, 95% CI) 1.5 [0.27, 8.34]
22 Reoperations 10 1116 Risk Ratio (M‐H, Fixed, 95% CI) 1.06 [0.54, 2.08]
22.1 ECTR vs standard OCTR 10 987 Risk Ratio (M‐H, Fixed, 95% CI) 1.57 [0.72, 3.43]
22.2 ECTR vs modified OCTR 1 129 Risk Ratio (M‐H, Fixed, 95% CI) 0.17 [0.02, 1.37]
23 Major complications 15 1508 Risk Ratio (M‐H, Random, 95% CI) 1.00 [0.38, 2.64]
23.1 ECTR vs standard OCTR 12 1392 Risk Ratio (M‐H, Random, 95% CI) 1.00 [0.38, 2.64]
23.2 ECTR vs modified OCTR 3 116 Risk Ratio (M‐H, Random, 95% CI) 0.0 [0.0, 0.0]
24 Minor complications 18 1786 Risk Ratio (M‐H, Random, 95% CI) 0.55 [0.38, 0.81]
24.1 ECTR vs standard OCTR 16 1601 Risk Ratio (M‐H, Random, 95% CI) 0.55 [0.37, 0.84]
24.2 ECTR vs modified OCTR 3 185 Risk Ratio (M‐H, Random, 95% CI) 0.64 [0.04, 9.37]
25 Total complications 19 1850 Odds Ratio (M‐H, Random, 95% CI) 0.60 [0.40, 0.90]
25.1 ECTR vs standard OCTR 17 1665 Odds Ratio (M‐H, Random, 95% CI) 0.60 [0.39, 0.90]
25.2 ECTR vs modified OCTR 3 185 Odds Ratio (M‐H, Random, 95% CI) 0.62 [0.04, 10.78]