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. 2014 Jan 31;2014(1):CD008265. doi: 10.1002/14651858.CD008265.pub2

Ferdinand 2002.

Methods Single‐centre RCT, bilateral CTS (each hand treated with each of the techniques)
Participants 25 participants (20 women, 5 men, mean age 54.9 years) with bilateral idiopathic CTS randomised to undergo ECTR to one hand and OCTR to the other. CTR was undertaken sequentially under the same anaesthetic
Interventions 1‐portal ECTR (Agee technique) vs OCTR
Outcomes Follow‐up at 6 weeks, 3 and 6 months and 1 year
Degree of resolution of symptoms, pain, tenderness (VAS), time of return to work, time of return to full activity, patient satisfaction
Notes In 3 hands allocated to ECTR, a conversion to OCTR was required due to inadequate view intraoperatively
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Randomisation was by standard computerised methods to
 determine which side underwent endoscopy
Allocation concealment (selection bias) Unclear risk Method of concealment not described
Blinding of participants and personnel (performance bias) 
 All outcomes High risk No information given. Participants and personnel could not be blinded.
Blinding of outcome assessment (detection bias) 
 All outcomes Low risk The participant concealed the wounds with adherent dressings before each assessment to ensure that the assessor continued to be blinded to the type of release which had been performed
Incomplete outcome data (attrition bias) 
 All outcomes Unclear risk In 3 hands allocated to ECTR, a conversion to OCTR was obtained due to inadequate view intraoperatively. However, there was no reference to ITT analysis
Selective reporting (reporting bias) Unclear risk No SDs were reported
Other bias Unclear risk The authors declare no benefits from commercial party
It is not clear whether baseline differences occurred