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Patient attrition flow. HRS standard presentation defined by including those with SCr <5 mg/dL and baseline ACLF grades 0–2 and excluding those with MELD scores≥35 if listed for transplant. ACLF, acute-on-chronic liver failure; HRS, hepatorenal syndrome; MELD, model for end-stage liver disease; RRT, renal replacement therapy; SCr, serum creatinine.
