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. 2023 Dec 7;99:104903. doi: 10.1016/j.ebiom.2023.104903

Fig. 5.

Fig. 5

Enhancement of Nabs against XBB.1.9.1 and shifting of immune imprinting after XBB reinfection. (A) Examination of immune imprinting after BA.5 infection. The Nab titers against WT, BA.5, and XBB.1.9.1 at D14 post infection were measured, and the ratios compared to XBB.1.9.1 were analyzed (n = 24). (B) To identify the capacity of combating immune imprinting of XBB reinfection, the ratios of Nabs between WT, BA.5, and XBB.1.9.1 were monitored at D14 post XBB reinfection (n = 10). (C) Kinetic analysis of Nabs against WT, BA.5, and XBB.1.9.1 for 12 reinfected individuals to investigate the changes in humoral immunity from BA.5 infection to XBB reinfection. The Mann–Whitney test was employed for comparing central tendencies of every two groups, ns, not significant; ∗∗P < 0.01, ∗∗∗P < 0.001, ∗∗∗∗P < 0.0001.