Table 2.
Average estimated total intracranial volume, whole hippocampal, and hippocampal subfield volumes in CN-NC, CN-C, MCI, and AD groups.
| CN-NC (n = 116) | CN-C (n = 28) | MCI (n = 90) | AD (n = 145) | |
|---|---|---|---|---|
| Mean ± SD | Mean ± SD | Mean ± SD | Mean ± SD | |
| eTIV | 1524.78 ± 174.86 | 1508.12 ± 148.74 | 1524.27 ± 186.51 | 1532.43 ± 176.84 |
| Left whole hippocampus | 3228.52 ± 375.37 | 3089.92 ± 460.14 | 3031.91 ± 473.25 | 2490.64 ± 446 |
| Left CA1 | 598.81 ± 77 | 573.24 ± 99.1 | 567.94 ± 97.55 | 462.93 ± 87.21 |
| Left CA3 | 200.92 ± 32.35 | 193.96 ± 35.3 | 184.6 ± 33.76 | 159.51 ± 35.95 |
| Left CA4 | 232.54 ± 30.28 | 222.24 ± 35.37 | 216.36 ± 34.03 | 184.23 ± 34.79 |
| Left subiculum | 412.19 ± 52.74 | 390.93 ± 67.31 | 383.3 ± 64.87 | 307.77 ± 61.9 |
| Left presubiculum | 295.86 ± 43.92 | 284.05 ± 52.14 | 286.45 ± 52.4 | 224.29 ± 45.93 |
| Left GC-DG | 284 ± 42.48 | 270.96 ± 56.17 | 265.46 ± 50.35 | 218.31 ± 50.57 |
| Left molecular layer | 516.95 ± 63.51 | 491.16 ± 81.93 | 482.87 ± 78.78 | 388.86 ± 73.11 |
| Left parasubiculum | 65.86 ± 14.86 | 65.07 ± 17.37 | 69.22 ± 19.06 | 58.31 ± 16.9 |
| Left hippocampal tail | 520.06 ± 73.61 | 511.36 ± 74.25 | 481.69 ± 88.41 | 415.34 ± 77.97 |
| Left HATA | 57.2 ± 10.81 | 51.78 ± 10.62 | 51.85 ± 12.31 | 43.36 ± 12.45 |
| Left fimbria | 62.21 ± 20.29 | 53.21 ± 21.8 | 60.71 ± 22.77 | 38.85 ± 21.41 |
| Left hippocampal fissure | 159.43 ± 31.53 | 163.9 ± 25.62 | 158.71 ± 31.14 | 146.01 ± 28.53 |
| Right whole hippocampus | 3326.65 ± 369.21 | 3166.12 ± 428.79 | 3133.09 ± 472.91 | 2647.75 ± 450.73 |
| Right CA1 | 635.34 ± 85.04 | 604.67 ± 91.38 | 599.22 ± 101.79 | 503.15 ± 94.47 |
| Right CA3 | 224.77 ± 34.3 | 213.86 ± 34.92 | 205.22 ± 37.63 | 180.99 ± 41.59 |
| Right CA4 | 244.5 ± 30.3 | 231.55 ± 29.95 | 227.57 ± 35.13 | 202.17 ± 38 |
| Right subiculum | 405.49 ± 51.1 | 385.55 ± 67.15 | 383.51 ± 64.84 | 313.74 ± 56.54 |
| Right presubiculum | 276.33 ± 38.23 | 263.18 ± 52.9 | 269.56 ± 47.6 | 214.62 ± 37.2 |
| Right GC-DG | 305.14 ± 44.71 | 287.66 ± 46.36 | 280.68 ± 52.09 | 241.58 ± 54.27 |
| Right molecular layer | 531.74 ± 64.29 | 504.61 ± 74.8 | 498.04 ± 79.14 | 414.63 ± 76.72 |
| Right parasubiculum | 62.54 ± 13.26 | 59.87 ± 12.91 | 64.31 ± 15.31 | 53.48 ± 14.24 |
| Right hippocampal tail | 549.19 ± 73.95 | 528.18 ± 68.47 | 518.85 ± 84.24 | 455.88 ± 82.69 |
| Right HATA | 61.06 ± 10.3 | 57.61 ± 10.95 | 52.91 ± 12.82 | 45.49 ± 11.57 |
| Right fimbria | 55.55 ± 18.87 | 52.68 ± 21.61 | 54.49 ± 22.13 | 36.36 ± 19.73 |
| Right hippocampal fissure† | 167.62 ± 30.97 | 172.8 ± 28.9 | 167.45 ± 30.43 | 159.63 ± 31.45 |
Mean and standard deviation of subfield and total hippocampal volumes in mm3. †No significant group differences after the FDR correction.