Table 3.
Stratified analysis of rs1595066 and GDM risk.
| Variablesa | CC/CT (Case/Control) | TT (Case/Control) | Adjusted OR (95%CI) | P b | P c |
|---|---|---|---|---|---|
| Age (years) | 0.339 | ||||
| ≤30.09 | 219/403 | 20/46 | 0.83 (0.47–1.47) | 0.515 | |
| >30.09 | 268/164 | 22/27 | 0.45 (0.24–0.84) | 0.013 | |
| Pre-BMI (Kg/m2) | 0.050 | ||||
| ≤22.23 | 214/385 | 19/48 | 0.72 (0.41–1.30) | 0.281 | |
| >22.23 | 272/181 | 23/25 | 0.52 (0.28–0.98) | 0.042 | |
| SBP (mmHg) | 0.380 | ||||
| ≤110.08 | 235/324 | 20/48 | 0.55 (0.31–0.98) | 0.043 | |
| >110.08 | 252/243 | 22/25 | 0.73 (0.38–1.43) | 0.363 | |
| DBP (mmHg) | 0.010 | ||||
| ≤69.53 | 239/301 | 21/24 | 0.57 (0.32–1.03) | 0.062 | |
| >69.53 | 248/266 | 21/32 | 0.67 (0.35–1.27) | 0.218 | |
| FPG (mmol/L) | <0.001 | ||||
| ≤4.79 | 194/498 | 12/67 | 0.40 (0.20–0.78) | 0.007 | |
| >4.79 | 293/69 | 30/6 | 1.12 (0.44–2.88) | 0.814 | |
| 1 h PG (mmol/L) | 0.050 | ||||
| ≤8.26 | 111/445 | 10/62 | 0.57 (0.28–1.18) | 0.129 | |
| >8.26 | 376/122 | 32/11 | 0.94 (0.45–1.96) | 0.861 | |
| 2 h PG (mmol/L) | 0.873 | ||||
| ≤7.11 | 140/467 | 10/63 | 0.47 (0.23–0.98) | 0.043 | |
| >7.11 | 347/100 | 32/10 | 0.88 (0.41–1.89) | 0.742 | |
| HbA1c (%) | <0.001 | ||||
| ≤5.20 | 176/419 | 13/56 | 0.51 (0.27–0.97) | 0.04 | |
| >5.20 | 311/148 | 29/17 | 0.75 (0.38–1.48) | 0.412 | |
| TG (mmol/L) | 0.137 | ||||
| ≤2.54 | 251/355 | 24/46 | 0.64 (0.36–1.12) | 0.118 | |
| >2.54 | 236/212 | 18/27 | 0.60 (0.31–1.17) | 0.134 |
a, Variables’ stratification was based on their mean value, respectively; b, Adjusted for age, pre-BMI in logistic regression models; c, Test for multiplicative interaction obtained from logistic regression models.
Bold values indicate that the differences are statistically significant.