Figure 2.

Radioactive substance uptakes in lung primary tumors and metastatic lesions in PET imaging with two tracers. (A) Representative (Case No. 1) PET imaging results obtained with [¹⁸F]FDG and [⁸⁹Zr]Zr-DFO-KN035 in lung primary tumor foci, lymph node metastatic lesions and bone metastatic lesion (cervical vertebra). Red arrows indicate the locations of primary cancer, lymph node metastatic lesions, and bone metastatic sites. (B) Statistical results of the target-to-muscle ratios of the SUVmax of each lesion in patients. Data are expressed as mean ± SD. One-way ANOVA was used. *p < 0.05 vs. [¹⁸F]FDG and ^###p < 0.001 vs. [⁸⁹Zr]Zr-DFO-KN035 at 55 h. Scale bar of SUV 0-12 for [¹⁸F]FDG and [⁸⁹Zr]Zr-DFO-KN035.