Table 2.

Regulation the expression of PROK1, PROKR1, and PROKR2 at maternal-fetal interface

Hormone	PROK1	PROKR1	PROKR2	Reference
Human chorionic gonadotropin	+	+	+	39
Progesterone	+	+		11,26,34
Estrogen	+	+		42
Dihydrotestosterone*	+			44
Insulin	+			43
Hypoxia	+	+		37
PPARγ	+	+	+	47

* Only effect with insulin.