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. 2023 Dec 11;10:1326833. doi: 10.3389/fmed.2023.1326833

Table 2.

Post-LEEP pathological findings.

Overall (n = 436) No residue (n = 258) Residue (n = 178) p-value
HPV infection before LEEP 0.12
Negative 87 (20%) 57 (13.1%) 30 (6.9%)
Positive 111 (25.5%) 68 (15.6%) 43 (9.9%)
Other 12 positive 108 (24.8%) 67 (15.4%) 41 (9.4%)
16/18 positive 130 (29.8%) 66 (15.1%) 64 (14.7%)
TCT before LEEP 0.72
NILM 124 (28.4%) 76 (17.4%) 48 (11%)
ASC-US 93 (21.3%) 59 (13.5%) 34 (7.8%)
ASC-H 67 (15.4%) 36 (8.3%) 31 (7.1%)
LSIL 47 (10.8%) 26 (6%) 21 (4.8%)
HSIL 105 (24.1%) 61 (14%) 44 (10.1%)
Pathology of LEEP 0.75
Normal or inflammation 57 (13.1%) 36 (8.3%) 21 (4.8%)
LSIL 46 (10.6%) 27 (6.2%) 19 (4.4%)
HSIL 324 (74.3%) 191 (43.8%) 133 (30.5%)
Suspected of an early invasive carcinoma 9 (2.1%) 4 (0.9%) 5 (1.1%)
LEEP internal cutting margin 0.001
Normal or inflammation 234 (53.7%) 152 (34.9%) 82 (18.8%)
LSIL 38 (8.7%) 27 (6.2%) 11 (2.5%)
HSIL 164 (37.6%) 79 (18.1%) 85 (19.5%)
LEEP outer cut margin 0.47
Normal or inflammation 294 (67.4%) 169 (38.8%) 125 (28.7%)
LSIL 45 (10.3%) 30 (6.9%) 15 (3.4%)
HSIL 97 (22.2%) 59 (13.5%) 38 (8.7%)
Gland involvement <0.001
NO 332 (76.1%) 254 (58.3%) 78 (17.9%)
Yes 104 (23.9%) 4 (0.9%) 100 (22.9%)

LEEP, loop electrosurgical excision procedure; TCT, Thinprep cytology test; NILM, Negative for intraepithelial lesion or malignancy; ASC-US, Atypical squamous cells of undetermined significance; ASC-H, Atypical squamous cells cannot exclude high-grade squamous intraepithelial lesion; LSIL, Low-grade squamous intraepithelial lesion; HSIL, High-grade squamous intraepithelial lesion.