Extended Table 5.

Model performance (AUC) of the original and extended VA models at the hospitalization level at VA and UM, by outcome stage, by sex

Outcome		VA Test AUC(95% Cl)			UM Test AUC(95% Cl)
	All	Female	Male	All	Female	Male
AKI-1+
Incidence	10.30%(5,158/50,031)	5.61 %(164/2,925)	10.60%(4,994/47,106)	16.10%(15,924/98,887)	13.94%(6,848/49,112)	18.23%(9,076/49,775)
Original VA model	0.7729(0.7664, 0.7794)	0.7700(0.7344, 0.8056)	0.7708(0.7642, 0.7774)	0.7227(0.7185, 0.727)	0.7231(0.7166, 0.7295)	0.7162(0.7104, 0.7220)
Extended VA model	0.7710(0.7645, 0.7775)	0.7643(0.7281, 0.8004)	0.7690(0.7623, 0.7756)	0.7393(0.7351, 0.7435)	0.7419(0.7356, 0.7482)	0.7311(0.7254, 0.7368)
AKI-2+
Incidence	1,50%(818/54,412)	1,04%(32/3,069)	1,53%(786/51,343)	3.91 %(3,874/99,149)	3.57%(1,758/49,228)	4.24%(2,116/49,921)
Original VA model	0.7708(0.7550, 0.7866)	0.8195(0.7478, 0.8912)	0.7689(0.7528, 0.7850)	0.6871(0.6786, 0.6956)	0.6705(0.6579, 0.6831)	0.7010(0.6896, 0.7125)
Extended VA model	0.7512(0.7354, 0.7671)	0.7965(0.7240, 0.8691)	0.7492(0.7330, 0.7654)	0.7665(0.7585, 0.7746)	0.7444(0.7321, 0.7566)	0.7853(0.7748, 0.7959)
AKI-3+
Incidence	0.83%(457/54,989)	0.71 %(22/3,100)	0.84%(435/51,889)	1.76%(1,745/99,199)	1,50%(737/49,258)	2.02%(1,008/49,941)
Original VA model	0.8215(0.8023, 0.8406)	0.8093(0.7136, 0.9050)	0.8223(0.8028, 0.8419)	0.7668(0.7541, 0.7795)	0.7128(0.6924, 0.7332)	0.8055(0.7898, 0.8213)
Extended VA model	0.8159(0.7962, 0.8356)	0.7913(0.6944, 0.8883)	0.8171(0.7970, 0.8373)	0.8287(0.8173, 0.8401)	0.7832(0.7642, 0.8022)	0.8613(0.8476, 0.8750)
AKI-3D
Incidence	0.29%(163/55,745)	0.29%(9/3,119)	0.29%(154/52,626)	0.23%(225/99,235)	0.19%(96/49,276)	0.26%(129/49,959)
Original VA model	0.9577(0.9448, 0.9706)	0.9227(0.7766, 1.0)	0.9593(0.9490, 0.9697)	0.9675(0.9587, 0.9762)	0.9696(0.9589, 0.9803)	0.9662(0.9526, 0.9799)
Extended VA model	0.9455(0.9259, 0.9651)	0.9231(0.7788, 1.0)	0.9464(0.9275, 0.9653)	0.9651(0.9561, 0.9741)	0.9669(0.9555, 0.9784)	0.9636(0.9439, 0.9774)