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. 2023 Nov 20;14(6):2925–2938. doi: 10.1002/jcsm.13377

Figure 4.

Figure 4

MiR‐92b overexpression in skeletal muscle reduced the exercise capacity. (A) Body weight (BW) changes over time of WT and miR‐92b overexpression (M92OE) mice (n = 6). (B) Body mass measured by MRI,amd weights of four muscle types, Gas, Sol, extensor, TA, and EDL from WT or M92OE mice (n = 6). (C) Blood glucose during ITT (left panel) and GTT (right panel) (n = 6). (D) The glycogen level of WT and M92OE mice before and after running exhaustion (n = 6). (E) The lactate level of WT and M92OE mice before and after running exhaustion (n = 6). (F) The running time (left) and distance (right) to exhaustion of WT and M92OE mice (n = 6). All results are expressed as means ± SD. *P < 0.05, **P < 0.01, ***P < 0.001, by unpaired Student's t test.