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. 2023 Nov 20;14(6):2925–2938. doi: 10.1002/jcsm.13377

Figure 5.

Figure 5

Absent of miR‐92b improved insulin resistance and enhanced the exercise capacity in diabetic mice. (A) Body weight (BW) changes over time of WT or M92KO mice made in diabetes model (n = 6). (B) Body mass measured by MRI in diabetic mice (n = 6). (C) Weights of four muscle types, Gas, Sol, extensor, TA, and EDL from diabetic mice (n = 6). (D) Blood glucose during ITT (left panel) and GTT (right panel) (n = 6). (E) The glycogen level (left and middle) and lactate level (right) of WT and M92KO mice before and after running exhaustion (n = 6). (F) The forelimb grip strength (left), and the running time (right) and distance (middle) to exhaustion of WT and M92KO mice (n = 6). All results are expressed as means ± SD. *P < 0.05, **P < 0.01, ***P < 0.001, by unpaired Student's t test.