Table 4.

Rate of change of appendicular lean mass (kg) and appendicular lean mass index (kg/m²) in DMD patients per 4 genotypes of DMD from ages 5 to 23 years.

	1: Exon 1–30		2: Exon 31–44		3: Exon 45–62		4: Exon 63–79		P‐values
Age (years)	Estimate	SE	Estimate	SE	Estimate	SE	Estimate	SE	1 v 2	1 vs. 3	1 vs. 4	2 vs. 3	2 vs. 4	3 vs. 4
ALM
5 to <7	0.68	0.12	0.72	0.22	0.62	0.07	0.80	0.28	0.8616	0.7200	0.6734	0.6842	0.8103	0.5378
7 to <10	0.42	0.05	0.57	0.09	0.42	0.03	0.55	0.10	0.1288	0.9143	0.2391	0.0868	0.8721	0.1886
10 to <14	0.43	0.03	0.35	0.05	0.19	0.02	−0.06	0.09	0.1802	<0.0001	<0.0001	0.0017	<0.0001	0.0070
14 to <20	0.09	0.04	0.01	0.04	0.00	0.03	0.02	0.08	0.1836	0.0481	0.4520	0.8490	0.8794	0.7716
≥20	0.66	0.20	−0.73	0.21	−0.78	0.12	−0.72	1.67	<0.0001	<0.0001	0.4108	0.8261	0.9966	0.9712
ALMI
5 to <7	0.16	0.05	0.18	0.09	0.16	0.04	0.36	0.15	0.8404	0.9659	0.2253	0.8514	0.3252	0.2196
7 to <10	0.04	0.02	0.10	0.04	0.01	0.01	0.11	0.06	0.1854	0.1423	0.3056	0.0173	0.9027	0.0933
10 to <14	−0.04	0.01	−0.09	0.02	−0.09	0.01	−0.45	0.05	0.0313	0.0115	<0.0001	0.7975	<0.0001	<0.0001
14 to <20	−0.12	0.02	−0.15	0.02	−0.09	0.01	−0.10	0.04	0.1410	0.1665	0.6245	0.0050	0.1996	0.8730
≥20	0.37	0.09	−0.21	0.09	−0.32	0.07	−0.14	0.89	<0.0001	<0.0001	0.5664	0.3351	0.9398	0.8466

ALM, appendicular lean mass; ALMI, appendicular lean mass index; BMD, Becker muscular dystrophy; DMD, Duchenne muscular dystrophy; SE, standard error.