Table 2.
Top 20 reactions based on the preferred terms of the MedDRA coding system (N=32,857)
| Adverse drug reaction | N | (%) |
| Angioedema | 7,513 | (22.9) |
| Urticaria | 4,902 | (14.9) |
| Maculo-papular rash | 3,556 | (10.8) |
| Periorbital edema | 3,433 | (10.4) |
| Rash | 3,249 | (9.9) |
| Pruritus | 1,903 | (5.8) |
| Anaphylactic reaction | 1,873 | (5.7) |
| Rash erythematous | 1,133 | (3.4) |
| Face edema | 1,121 | (3.4) |
| Edema mouth | 1,079 | (3.3) |
| Dyspnea | 853 | (2.6) |
| Fixed eruption | 840 | (2.6) |
| Anaphylactic shock | 798 | (2.4) |
| Chest pain | 690 | (2.1) |
| Edema | 296 | (0.9) |
| Stevens-Johnson syndrome | 223 | (0.7) |
| Mouth ulceration | 208 | (0.6) |
| Palpitations | 198 | (0.6) |
| Conjunctivitis | 191 | (0.6) |
| Edema peripheral | 173 | (0.5) |
MedDRA: Medical Dictionary for Regulatory Activities
One or more adverse drug reactions could be selected.