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. 2023 Nov;85(4):668–681. doi: 10.18999/nagjms.85.4.668

Table 5.

Reporting odd ratio of new signals of NSAIDs

Drug Preferred terma Number of reportsb ROR 95% CI
Etoricoxib oliguria 4 22.97 8.16–64.65
Parecoxib cardiac arrest 4 15.53 5.77–41.79
Etoricoxib pharyngeal edema 3 12.83 3.99–41.23
Sulindac cheilitis 5 12.48 5.14–30.27
Etoricoxib genital ulceration 10 8.94 4.74–16.85
Parecoxib lacrimation increased 3 8.94 2.86–27.91
Celecoxib hiccups 4 7.63 2.81–20.70
Parecoxib choking 6 6.29 2.81–14.06
Ibuprofen lacrimation increase 62 5.01 3.79–6.63
Diclofenac laryngeal edema 5 4.41 1.73–11.26
Parecoxib flushing 16 3.97 2.42–6.50
Etoricoxib thermal burn 15 3.85 2.31–6.42
Celecoxib choking 13 3.21 1.86–5.55
Diclofenac lacrimation increase 24 2.68 1.77–4.07
Aspirin choking 11 2.50 1.38–4.53
Ibuprofen choking 83 2.08 1.66–2.61
Meloxicam fixed eruption 96 2.05 1.67–2.51
Meloxicam eczema 13 1.89 1.09–3.26
Mefenamic acid fixed eruption 205 1.78 1.55–2.05
Etoricoxib cheilitis 17 1.71 1.06–2.76
Mefenamic acid anaesthesia oral 29 1.68 1.16–2.42
Etoricoxib anaesthesia oral 20 1.67 1.07–2.60
Celecoxib anaesthesia oral 19 1.64 1.04–2.58
Aspirin fatigue 37 1.41 1.02–1.95

aPreferred term of adverse events by the MedDRA coding system.

bAll the reports containing NSAIDs that were identified as suspected or drug interaction were extracted from the Thai VigiBase, and each report may contain more than one event or drug.