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. 2024 Jan 1;33(1):e4865. doi: 10.1002/pro.4865

FIGURE 5.

FIGURE 5

Improved subunit modeling enhances antibody–antigen complex modeling success. Antibody–antigen modeling success of AlphaFold by utilizing (a) templates identified through the default template search protocol, (b) bound antibody and antigen chains as templates, (c) bound antibody and default antigen chains (identified by the default search protocol) as templates. Benchmarking was performed on a total of 100 antibody–antigen complexes. The success rate was calculated based on the percentage of cases that had at least one model among their top N predictions that met a specified level of CAPRI accuracy. Bars are colored by CAPRI accuracy criteria.