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. 2023 Dec 22;67:102393. doi: 10.1016/j.eclinm.2023.102393

Table 3.

Use of mould-active anti-fungal drugs after alloSCT in the subgroup of patients with available comprehensive information on drug use.

IA pre alloSCT
Total (N = 1152)
No (N = 1083)
Yes (N = 69)
N (%) N (%) N (%)
Any anti-mould drug given day 0- day +99
 No 398 (36.7) 8 (11.6) 406 (35.2)
 Yes 685 (63.3) 61 (88.4) 746 (64.8)
Posaconazole given day 0 to +99
 No 785 (72.5) 45 (65.2) 830 (72.0)
 Yes 298 (27.5) 24 (34.8) 322 (28.0)
Voriconazole given day 0–day +99
 No 841 (77.7) 42 (60.9) 883 (76.6)
 Yes 242 (22.3) 27 (39.1) 269 (23.4)
Ambisome given day 0–day +99
 No 877 (81.0) 46 (66.7) 923 (80.1)
 Yes 206 (19.0) 23 (33.3) 229 (19.9)
Echinocandin given day 0–day +99
 No 937 (86.5) 61 (88.4) 998 (86.6)
 Yes 146 (13.5) 8 (11.6) 154 (13.4)
Amphotericin given day 0–day +99
 No 1027 (94.8) 69 (100.0) 1096 (95.1)
 Yes 56 (5.2) 0 (0.0) 56 (4.9)
Isavuconazole given day 0–day +99
 No 1054 (97.3) 65 (94.2) 1119 (97.1)
 Yes 29 (2.7) 4 (5.8) 33 (2.9)

N = 924
N = 56
N = 980
Any anti-mould drug given day +100day +365
 No 520 (56.3) 19 (33.9) 539 (55.0)
 Yes 404 (43.7) 37 (66.1) 441 (45.0)
Posaconazole given day +100–day +365
 No 720 (77.9) 46 (82.1) 766 (78.2)
 Yes 204 (22.1) 10 (17.9) 214 (21.8)
Voriconazole given day +100–day +365
 No 765 (82.8) 37 (66.1) 802 (81.8)
 Yes 159 (17.2) 19 (33.9) 178 (18.2)
Ambisome given day +100–day +365
 No 833 (90.2) 42 (75.0) 875 (89.3)
 Yes 91 (9.8) 14 (25.0) 105 (10.7)
Echinocandin given day +100–day +365
 No 863 (93.4) 51 (91.1) 914 (93.3)
 Yes 61 (6.6) 5 (8.9) 66 (6.7)
Amphotericin given day +100–day +365
 No 902 (97.6) 56 (100.0) 958 (97.8)
 Yes 22 (2.4) 0 (0.0) 22 (2.2)
Isavuconazole given day +100–day +365
 No 897 (97.1) 52 (92.9) 949 (96.8)
 Yes 27 (2.9) 4 (7.1) 31 (3.2)