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. 2023 Dec 12;13:1216536. doi: 10.3389/fcimb.2023.1216536

Table 3.

Clinical characteristics of patients need intensive care unit between the pandemic year 2021 and pre-pandemic years 2016−2019 for RSV.

Pre-pandemic years
(n=376)
Pandemic year 2021
(n=66)
P value
Male sex, % 248 (66.0) 42 (63.6) 0.72
Median age, m 3 (2-6) 7 (2-24) <0.001
Age groups, %
 0-5m 272 (72.3) 27 (40.9) <0.001
 6-11m 47 (12.5) 12 (18.2) 0.21
 12-23m 18 (4.8) 6 (9.1) 0.16
 2-4y 32 (8.5) 12 (18.2) 0.02
 5-15y 7 (1.9) 9 (13.6) <0.001
Comorbidities, % 106 (28.2) 23 (34.9) <0.001
 Cardiovascular  diseases 64 (17.0) 6 (9.1) <0.001
 Respiratory diseases 26 (6.9) 5 (7.6) 0.85
 Neurologic and  muscular diseases 18 (4.8) 3 (4.5) 0.93
 Malignancy 6 (1.6) 8 (12.1) <0.001
 Metabolic diseases 6 (1.6) 2 (3.0) 0.34
 Immunologic 3 (0.8) 2 (3.0) 0.16
 Gastrointestinal 1 (0.3) 1 (1.5) 0.28
 Renal 1 (0.3) 1 (1.5) 0.28
Complications during admission, %
 Pneumothorax 8 (2.1) 3 (4.5) 0.22
 Pleural fluid 19 (5.1) 3 (4.5) 0.86
 Meningitis 4 (1.1) 1 (1.5) 0.56
 Seizure 4 (1.1) 2 (3.0) 0.22
 Apnea 12 (3.2) 2 (3.0) 0.95
Oxygen support, %
 High-flow  nasal canula 150 (39.9) 24 (36.4) 0.59
 Mechanical  Ventilation 49 (13) 11 (16) 0.44
Death, % 1 (0.3) 5 (7.6) <0.001*

P<0.001 means the difference is statistically significant.