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. 2023 Oct 30;149(1):28–35. doi: 10.1161/CIRCULATIONAHA.123.066213

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© 2023 The Authors.

Circulation is published on behalf of the American Heart Association, Inc., by Wolters Kluwer Health, Inc. This is an open access article under the terms of the Creative Commons Attribution Non-Commercial-NoDerivs License, which permits use, distribution, and reproduction in any medium, provided that the original work is properly cited, the use is noncommercial, and no modifications or adaptations are made.

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Figure 2. — Inflammation determines risk of cardiovascular death at both high and low levels of LDLC. Joint analysis of hsCRP (≥ or <2 mg/L) and LDLC (≥ or <130 mg/dL) as predictors of cardiovascular death among 13 970 statin-intolerant patients. Hazard ratios and 95% CIs adjusted for age, sex, ethnicity, region, diabetes, body mass index, estimated glomerular filtration rate, blood pressure, alcohol use, smoking status, known atherosclerotic disease, and randomized treatment assignment. hsCRP indicates high-sensitivity C-reactive protein; and LDLC, low-density lipoprotein cholesterol.