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. Author manuscript; available in PMC: 2023 Dec 27.
Published in final edited form as: Lab Invest. 2019 Jan 18;99(5):708–721. doi: 10.1038/s41374-018-0168-7

Figure 4. Protein and DNA extractability is increased from Theralin fixed tissue.

Figure 4.

Patient matched bone tumor samples (n=7) were either Theralin fixed, Theralin fixed and decalcified, or formalin fixed and decalcified. An equal number of tumor cells were laser-capture microdissected and cell lysates printed on reverse phase protein microarrays. Formalin fixation followed by decalcification yielded significantly less protein and DNA than Theralin fixation with or without decalcification. (boxes = 25th to 75th percentile with whiskers going to the smallest and largest value, Decal = decalcification, NBF = formalin fixation, * p<0.05, ** p<0.005)