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. Author manuscript; available in PMC: 2023 Dec 27.
Published in final edited form as: Lab Invest. 2019 Jan 18;99(5):708–721. doi: 10.1038/s41374-018-0168-7

Figure 5. The measurable protein level per microdissected tumor area is reduced indiscriminately across protein classes following formalin fixation.

Figure 5.

Patient matched bone tumor samples (n=7) were either Theralin fixed (dark gray bar), Theralin fixed and decalcified (white bar), or formalin fixed and decalcified (light gray bar) and tumor cells laser-capture microdissected. Protein levels were measured using reverse phase protein microarrays and normalized to the microdissected area. (boxes = 25th to 75th percentile with whiskers going to the smallest and largest value, # p<0.05 versus Theralin fixation, & p<0.05 versus Theralin fixation and decalcification)