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. 2023 Jul 24;11(7):1553–1564. doi: 10.14218/JCTH.2023.00118

Fig. 7. iCCA with multiple histological subtypes.

Fig. 7

(A) Large duct type iCCA (upper left) and small duct type iCCA (bottom right) components in the same tumor; (B) Small duct type iCCA (left) and DPM pattern iCCA (right) components in the same tumor; (C) IHC staining for CRP shows strong positive results on small duct type iCCA (left) components and weak positive results on DPM pattern iCCA (right) components. CRP, C-reactive protein; DPM, ductal plate malformation; iCCA, intrahepatic cholangiocarcinoma; IHC, immunohistochemistry.