Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Dec 27;13:22974. doi: 10.1038/s41598-023-49751-5

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Effects of fucoxanthin on the expression of PI3K/Akt/Nrf-2 in H₂O₂-treated PL-MSCs. Quantitative real-time RT-PCR showed the expression of PI3K (a), Akt (b), and Nrf-2 (c) in PL-MSCs after 48 h of co-treatment with 750 μM H₂O₂ and fucoxanthin. (d) Western blot analysis showed the expression of PI3K/Akt/Nrf-2. The blotted membranes were cropped before hybridization with primary antibodies. The original blots of (d) are shown in Supplementary Fig. 4–6. (e)–(g) Relative protein expression level of p-PI3K/PI3K, p-Akt/Akt, and Nrf-2 in PL-MSCs after 48 h of co-treatment with 750 μM H₂O₂ and fucoxanthin. Data are presented as mean ± SEM, n = 3. Statistical significance was tested using the pair T-test. ^#p ≤ 0.001 vs. PL-MSCs cultured in the completed DMEM medium. *p ≤ 0.05 vs. H₂O₂-treated PL-MSCs without fucoxanthin. ^$p ≤ 0.05 vs. PL-MSCs cultured in the completed DMEM medium.