Table 3.
Fold change in gene expression of fucoxanthin-treated PL-MSCs compared to untreated PL-MSCs under oxidative stress.
| Up-regulated Genes |
Gene description | Fold change | P value |
|---|---|---|---|
| MKI67 | Antigen Ki-67 | 17.82 | 0.035 |
| HJURP | Holliday junction recognition protein | 11.25 | 0.006 |
| GTSE1 | G2 And S-Phase Expressed 1 | 9.88 | 0.016 |
| PLK1 | Polo-like kinase 1 | 8.60 | 0.001 |
| CENPA | Centromere Protein A | 8.10 | 0.003 |
| CDC20 | Cell division cycle protein 20 | 7.85 | 0.003 |
| NCAPH | Non-SMC Condensin I Complex Subunit H | 6.71 | 0.013 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | 6.16 | 0.001 |
| UBE2C | Ubiquitin conjugating enzyme E2 C | 5.73 | 0.002 |
| EME1 | Essential meiotic structure-specific endonuclease 1 | 5.68 | 0.015 |
| Down-regulated Genes |
Gene description | Fold change | P value |
|---|---|---|---|
| UPP1 | Uridine phosphorylase 1 | − 3.030 | 0.003 |
| FDXR | Ferredoxin Reductase | − 2.890 | 0.003 |
| PNP | Purine Nucleoside Phosphorylase | − 2.700 | 0.044 |
| ERN1 | Endoplasmic reticulum to nucleus signaling 1 | − 2.500 | 0.001 |
| RPS6KA1 | Ribosomal protein S6 kinase alpha 1 | − 2.140 | 0.028 |
| SLC3A2 | Solute carrier family 3 member 2 | − 2.040 | 0.008 |
| SQSTM1 | Sequestosome 1 | − 1.930 | 0.007 |
| TRAF1 | Tumor necrosis factor receptor-associated factor 1 | − 1.830 | 0.047 |
| TIGAR | TP53-inducible glycolysis and apoptosis regulator | − 1.770 | 0.017 |
| CTSL | Cathepsin L | − 1.650 | 0.010 |