Increased retrograde-labeled cells in DRG of ACLT induced OA animals in large-sized neurons and slightly reduced by the effect of LIPUS treatment (A–B) The percentage of FG-positive and FG-positive CGRP-positive neurons is based on its soma size (C) The percentage of FG-positive neurons based on its soma size stratified by subgroups, small (<600 μm2), medium (>600 μm2, <1200 μm2), and large (>1200 μm2) (D) the percentage of CGRP-positive neurons in total FG-positive neurons (E) the percentage of FG-positive and CGRP-positive neurons (statistical differences only shown vs. Sham). ∗:p < 0.05, ∗∗:p < 0.01, a:p < 0.05 vs. Sham small, b:p < 0.05 vs. Sham medium, c:p < 0.05 vs. Sham large. Results are shown as mean ± SD.