Forest plots illustrating the findings for coronary artery calcification (a) meta-analysis of 4 studies for the association of CAC severity with risk of future Coronary Heart Disease Events (n=21717). Studies included in this analysis: Erbel,46 LaMonte,58 Bhatia,41 Hoffman64. For the Heinz Nixdorf study relative risk (RR) was used. For the Heinz Nixdorf and Cooper Clinic studies, results are presented per unit of log-transformed CAC. For MESA studies, results are presented per 1-standard deviation increase in log-transformed CAC.
(b) a meta-analysis of the association of category of CAC (low moderate or severe) with risk of future events Coronary Heart Disease Events. The number of studies in each category ranged from 2 (n=10190) to 4 (n=16144). For the Heinz Nixdorf study relative risk (RR) was used.