Table 9:
Population-based studies assessing ABI as a predictor of future cardiovascular events or death published since the ABI Collaboration in 2008115
| Study [ref] | Country, Year of publication | Population (% men, mean age) | Follow-up (years) | Outcome (n=) |
Measurement | Adjusted HR (95% CI)* | Ethnicity and/or other comments |
|---|---|---|---|---|---|---|---|
| MESA159 | USA 2019 | 6669 (49%, 62y) | 14.2 | CVD (288) |
ABI<0.9 | 2.15 [1.55,3.44] |
Abstract only. Lower ABI of lower leg |
| NHANES160 | USA 2021 | 7571 (N/A, 60y) | 8 | CVD (204) |
ABI<0.9 | 3.92 [1.81–5.28] |
Abstract only |
| ARTPER116 | Spain 2018 | 2716 (43%, 62y) | 9 | CV events & death (187) | ABI<0.9 | 2.55 [1.53–4.24] |
|
| REGICOR161 | Spain 2017 | 5679 (54%, 55.4y) | 6.2 | CVD (59) |
ABI>1.4 | 3.1 [1.95–6.48] |
|
| REGICOR123 | Spain 2015 | 5248 (45%, 53.7y) | 5.9 | CV events (175) |
ABI<0.9 | 3.03 [1.86,4.95] |
5248 (45%) |
| ARIC121 | USA 2012 | 1594 (44%. 53.8y) | 10 | CV events (659) |
ABI<0.9 | 1.18 [1.10,1.27] |
24% black |
| Hoorn 162 |
Holland 2012 |
624 (49.5%, 64.7y) | 17.2 | CVD (85) | ABI<0.9 | 2.57 [1.50–4.40] |
Similar HR with/without type 2 diabetes |
| MESA 122 |
USA 2011 |
6647 (49%, 62.1y) | 5.3 | CV events (317) |
ABI>1.4 ABI<1 |
1.95 [1.0–3.43] 1.77 [1.31–2.40] |
White 38.8% Chinese 12.7% African-American 25.6% Hispanic 23.1% Consistent findings across Hispanics, Chinese, Whites, Blacks. Adds predictive value to FRS |
CVD cardiovascular death, CV cardiovascular