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. 2023 Dec 13;9:e50110. doi: 10.2196/50110

Table 3.

Odds ratios considering each of the 50 different global Shapley additive explanation value distributions from data covering the period 2001-2019.

ATCa class ATC description Odds ratiob (95% CI) P value
c07aa05 Propranolol 1.94 (1.37-2.77) <.001
n05cm09 Valerian 1.61 (1.15-2.25) .01
c09aa02 Enalapril 1.34 (0.9-1.98) .15
d11ax18 Diclofenac 1.33 (1.04-1.71) .03
c10aa01 Simvastatin 1.3 (1-1.69) .05
g01aa10 Clindamycin 1.22 (0.94-1.59) .14
s01aa01 Chloramphenicol 1.19 (1.02-1.4) .03
a02ba03 Famotidine 1.17 (0.97-1.42) .10
r03ac03 Terbutaline 1.17 (0.86-1.59) .32
b03ad01 Ferrous amino acid complex 1.15 (0.95-1.4) .16
a10ba02 Metformin 1.14 (0.66-1.96) .65
j01ce02 Phenoxymethylpenicillin 0.96 (0.82-1.11) .58
r01ba52 Pseuroephedrine, combination 0.86 (0.73-1.02) .07
s01ca01 Dexamethansone 0.8 (0.67-0.97) .02
d07ac13 Mometasone 0.79 (0.63-0.98) .04
d04aa13 Dimetindene 0.71 (0.54-0.92) .01
n06ab05 Paroxetine 0.33 (0.2-0.57) .001

aATC: Anatomical Therapeutic Chemical classification system.

bEffect estimates from conditional logistic regression accounting for the matched risk sets, with additional adjustment for the average frequency of physician visits and any history of diabetes, cardiovascular disease, or excess weight prior to the index date.