Table 2.
Logistic regression | Modified Poisson | |||||||
---|---|---|---|---|---|---|---|---|
Unadjusted OR | 95% CI | Adjusted OR | 95% CI | Unadjusted RR | 95% CI | Adjusted RR | 95% CI | |
COVID-19 coinfection | NA | NA | 2.15 | 1.26–3.68 | NA | NA | 1.44 | 1.01–2.06 |
Period | ||||||||
COVID-19 period | Reference | |||||||
Early pre-COVID-19 period | 0.85 | 0.72–0.99 | 0.89 | 0.76–1.05 | 0.91 | 0.80-1.03 | 0.94 | 0.82–1.07 |
Late pre-COVID-19 period | 0.78 | 0.64–0.94 | 0.82 | 0.67–1.00 | 0.86 | 0.73–1.00 | 0.88 | 0.75–1.04 |
Sex | ||||||||
Female | Reference | |||||||
Male | 0.83 | 0.56–1.23 | 0.83 | 0.56–1.23 | 0.90 | 0.66–1.22 | 0.90 | 0.66–1.22 |
Age | ||||||||
Age in decades over 40 | 1.07 | 1.01–1.13 | 1.07 | 1.02–1.13 | 1.04 | 1.00–1.09 | 1.04 | 1.00–1.09 |
Race | ||||||||
White | Reference | |||||||
Black | 1.03 | 0.88–1.20 | 1.03 | 0.88–1.20 | 1.02 | 0.91–1.15 | 1.02 | 0.91–1.14 |
Other | 0.72 | 0.40–1.29 | 0.73 | 0.40–1.30 | 0.82 | 0.52–1.30 | 0.83 | 0.52–1.31 |
Ethnicity | ||||||||
Non-Hispanic/Latino | Reference | |||||||
Hispanic/Latino | 1.02 | 0.82–1.27 | 1.02 | 0.82–1.27 | 1.01 | 0.86–1.20 | 1.01 | 0.85–1.20 |
Charlson Comorbidity Index | ||||||||
0–2 | Reference | |||||||
3–5 | 1.45 | 1.23–1.72 | 1.45 | 1.23–1.72 | 1.29 | 1.13–1.49 | 1.29 | 1.13–1.49 |
6+ | 2.11 | 1.78–2.50 | 2.11 | 1.78–2.50 | 1.62 | 1.41–1.86 | 1.62 | 1.41–1.86 |
Modified APACHE score | ||||||||
<50 | Reference | |||||||
50–59 | 2.37 | 1.91–2.95 | 2.36 | 1.90–2.93 | 2.15 | 1.76–2.63 | 2.15 | 1.76–2.62 |
60–74 | 4.26 | 3.48–5.22 | 4.25 | 3.47–5.20 | 3.35 | 2.79–4.02 | 3.34 | 2.79–4.02 |
75–84 | 10.89 | 8.40–14.13 | 10.89 | 8.39–14.13 | 5.77 | 4.69–7.08 | 5.76 | 4.69–7.07 |
85+ | 22.13 | 16.78–29.19 | 21.95 | 16.63–28.96 | 7.59 | 6.24–9.23 | 7.53 | 6.19–9.16 |
Missing | 7.52 | 6.22–9.08 | 7.48 | 6.19–9.04 | 4.80 | 4.06–5.68 | 4.79 | 4.05–5.66 |
Treatment administered within 48 h | ||||||||
Targeted treatment | Reference | |||||||
No targeted treatment | 1.84 | 1.59–2.13 | 1.84 | 1.59–2.13 | 1.43 | 1.29–1.60 | 1.43 | 1.28–1.60 |
Note. OR, odds ratio; CI, confidence interval; RR, relative risk.