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. 2023 Dec 15;3(1):e237. doi: 10.1017/ash.2023.455

Table 2.

Predictors of 30-d mortality among patients with Pseudomonas aeruginosa bloodstream infection (n = 6,714) with and without adjustment for COVID-19 coinfection

Logistic regression Modified Poisson
Unadjusted OR 95% CI Adjusted OR 95% CI Unadjusted RR 95% CI Adjusted RR 95% CI
COVID-19 coinfection NA NA 2.15 1.26–3.68 NA NA 1.44 1.01–2.06
Period
COVID-19 period Reference
Early pre-COVID-19 period 0.85 0.72–0.99 0.89 0.76–1.05 0.91 0.80-1.03 0.94 0.82–1.07
Late pre-COVID-19 period 0.78 0.64–0.94 0.82 0.67–1.00 0.86 0.73–1.00 0.88 0.75–1.04
Sex
Female Reference
Male 0.83 0.56–1.23 0.83 0.56–1.23 0.90 0.66–1.22 0.90 0.66–1.22
Age
Age in decades over 40 1.07 1.01–1.13 1.07 1.02–1.13 1.04 1.00–1.09 1.04 1.00–1.09
Race
White Reference
Black 1.03 0.88–1.20 1.03 0.88–1.20 1.02 0.91–1.15 1.02 0.91–1.14
Other 0.72 0.40–1.29 0.73 0.40–1.30 0.82 0.52–1.30 0.83 0.52–1.31
Ethnicity
Non-Hispanic/Latino Reference
Hispanic/Latino 1.02 0.82–1.27 1.02 0.82–1.27 1.01 0.86–1.20 1.01 0.85–1.20
Charlson Comorbidity Index
0–2 Reference
3–5 1.45 1.23–1.72 1.45 1.23–1.72 1.29 1.13–1.49 1.29 1.13–1.49
6+ 2.11 1.78–2.50 2.11 1.78–2.50 1.62 1.41–1.86 1.62 1.41–1.86
Modified APACHE score
<50 Reference
50–59 2.37 1.91–2.95 2.36 1.90–2.93 2.15 1.76–2.63 2.15 1.76–2.62
60–74 4.26 3.48–5.22 4.25 3.47–5.20 3.35 2.79–4.02 3.34 2.79–4.02
75–84 10.89 8.40–14.13 10.89 8.39–14.13 5.77 4.69–7.08 5.76 4.69–7.07
85+ 22.13 16.78–29.19 21.95 16.63–28.96 7.59 6.24–9.23 7.53 6.19–9.16
Missing 7.52 6.22–9.08 7.48 6.19–9.04 4.80 4.06–5.68 4.79 4.05–5.66
Treatment administered within 48 h
Targeted treatment Reference
No targeted treatment 1.84 1.59–2.13 1.84 1.59–2.13 1.43 1.29–1.60 1.43 1.28–1.60

Note. OR, odds ratio; CI, confidence interval; RR, relative risk.