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. 2023 Nov 20;10(36):2303457. doi: 10.1002/advs.202303457

Figure 1.

Figure 1

L. intestinalis relieved DSS‐induced chronic colitis. A) Fecal abundance of L. intestinalis was measured in wild‐type and G3 mice. B,C) Fecal abundance of L. intestinalis was measured in a control group, and murine DSS‐induced chronic colitis (B) or acute colitis (C). D) Fecal abundance of L. intestinalis was compared among mice treated without (Untreated), or with DSS accompanied by PBS, E. coli, or L. intestinalis (L. int) gavage respectively (n = 5). E–G) The pathology of colitis was evaluated among the control group (Untreated) and the three chronic colitis groups with PBS, E. coli, or L. intestinalis (L. int) gavage respectively by disease activity index (E), colon length (scale bar, 1 cm) (F) and histological score (scale bar, 100 µm) (G) (n = 5). Error bars indicate mean ± SEM. * p < 0.05; ** p < 0.01; *** p < 0.001; **** p < 0.0001. p values were based on Mann–Whitney test and one‐way ANOVA with post‐hoc test.