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. 2023 Dec 22;72(51):1357–1364. doi: 10.15585/mmwr.mm7251a1

FIGURE 2.

The figure is a timeline of the timing of viral rebound and resolution during SARS-CoV-2 infection among 22 patients.

Timing of viral rebound and resolution during SARS-CoV-2 infection among 22 patients*,† — February 1, 2020–November 29, 2023

* Median time to negative test result was defined as day of first negative viral test result (polymerase chain reaction or antigen) after initial positive test result. Viral rebound was defined as the first positive viral test result (polymerase chain reaction or antigen) after a negative test result. Resolution was defined as first negative viral test result after day 1 of viral rebound.

Timing and duration of viral rebound generated using data from 22 patients in three studies that used a virologic definition of rebound and had complete data: https://doi.org/10.1093/cid/ciac512, https://doi.org/10.1056/NEJMc2206449, and https://doi.org/10.1016/j.jinf.2022.06.011.