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. Author manuscript; available in PMC: 2023 Dec 28.
Published in final edited form as: Nature. 2023 Jun 21;618(7967):1078–1084. doi: 10.1038/s41586-023-06229-8

Fig. 3. The Lettuce core and its structure-guided minimization.

Fig. 3.

a, View of P1.1. b, Orthogonal view. c, View of P1.2 element of Lettuce. d, Orthogonal view of c. e, Fluorescence of site-directed mutants of P1.1 and P1.2 in the presence of DFHBI-1T, normalized to wild-type (mean ± s.d., n ≥ 3). Striped bar, A14T•T29, T15G•T28C mutant. f, Fluorescence of Lettuce constructs with shortened P1 in the presence of DFHBI-1T, normalized to wild-type (mean ± s.d., n ≥ 3). g, Schematic of circular permutation. h, Fluorescence of Lettuce constructs with permuted P1 (P1cp) in the presence of DFHBI-1T, normalized to wild-type (mean ± s.d., n ≥ 3). i, Fluorescence of Lettuce mutant A14T•T29, T15G•T28C and shortened P1cp in the presence of DFHBI-1T, normalized to wild-type (mean ± s.d., n ≥ 3).